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Torontos diverse population faces a range of skin concerns, from hyperpigmentation to seasonal dullness aggravated by the citys cold, dry winters

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A number of studies have provided indirect or circumstantial evidence for the collateral induction of autophagy and senescence 69,70,71,72

muciniphila , a bacterium important for maintaining gut barrier integrity, is decreased in both ALD mouse models and patients with AH.148 Additionally, patients with AH show elevated levels of cytolytic-positive faecal enterococci, which correlate with the severity of liver disease and mortality.149 These findings highlight the pivotal role of dysbiosis in driving the progression of liver disease through the gut-liver axis